The Best PRN & Part-Time Work from Home Nursing Jobs

PRN and part-time work from home nursing jobs? Yes, they exist! But they’re not as easy to snag as landing traditional PRN bedside nursing jobs. Whether you’re a Registered Nurse (RN), Licensed Practical or Vocational Nurse (LPN/LVN), or Nurse Practitioner (NP), finding and landing these roles takes more than just a quick job search and submitting your bedside nursing resume.

Most companies prioritize full-time hires first, making part-time and PRN spots not only harder to come by but also usually requiring prior experience. BUT knowing what to expect (and where to focus your search) can give you a serious edge!

If you’re set on working remotely without committing to full-time hours, these are the remote nursing specialties most likely to offer PRN or part-time schedules.

2. Case Management & Care Coordination

Part-time and PRN case management jobs exist, but they’re harder to land if you don’t already have direct experience in care coordination, utilization review, or discharge planning.

However, many nurses already have transferable experience without realizing it. If you’ve spent time:

• Coordinating discharge plans with social workers
• Arranging home health, DME, or follow-ups
• Handling insurance authorizations for treatments or hospital stays

…then you’ve been doing case management work, you just need to frame it correctly on your resume to match the job description.

Because these roles involve coordinating patient care across teams, managing insurance approvals, and ensuring patients have everything they need post-discharge, they tend to be more competitive. If you already have an active RN license and previous case management experience, you’ll have a better chance of landing one of these part-time roles.

Companies that have hired part-time or PRN case managers:

• Humana
• Centerwell
• Lucet
• Sutter Health

 3. Utilization Review (UR) & Prior Authorization

If you want to work behind the scenes, reviewing clinical documentation to determine medical necessity, insurance approvals, and denials, UR or prior authorization might be a great fit.

But here’s the challenge: Entry-level part-time positions are not the norm, so if you see one, don’t wait to apply! Companies will prioritze nurses who have direct experience in UR, prior auth, or insurance-based nursing for part-time hours.

If you’ve worked with MCG or InterQual guidelines, handled insurance approvals and denials, or assisted with medical necessity reviews, you’ll be in a stronger position to apply.

Want to stand out? Getting an MCG Certification can help. It’s not a guarantee, but it shows hiring managers you’re serious about the field. But there’s a catch-22 to getting this certification. You’re not eligible to take the exam unless an employer sponsors you.

BUT Case Management Institute (CMI) has partnered up with MCG Health to offer training so nurses can now obtain this certification without the need to be hired by an employer first! 

The CMI course that is approved by MCG Health is the Utilization Management and MCG Course.  Use code ‘andrea10‘ to get 10% off!

 Companies that have hired part-time or PRN UR nurses:

• Netsmart
• UnitedHealth Group
• Ensemble Health Partners
• Honor Health

4. Clinical Data Abstraction & Quality Improvement

This behind-the-scenes role helps healthcare organizations track quality measures, submit registry data, and support research efforts.

Most employers prefer full-time or seasonal hires first in these roles due to the training involved. Your best bet is to start full-time and transition later. For registry and research-based abstraction roles, hospitals are more likely to offer training than third-party companies.

Some common areas for data abstraction include:

• HEDIS & Healthcare Quality Reporting – Reviewing records to ensure compliance with HEDIS measures (seasonal work, Jan–May).
• Hospital Quality Registries – Submitting data to registries like NSQIP, Breast Cancer Surveillance, or Perinatal Quality Collaboratives.
• Clinical Research Data Collection – Extracting key study data from medical charts for research trials.
• More on data abstraction roles here

Flatiron Health previously hired nurses with strong oncology experience for flexible data abstraction roles, but in recent years, those openings have been rare.

Companies that have hired part-time or PRN clinical data abstractors:

• Carta Healthcare
• AdvantMed
• Q-Centrix
• Optum | UHG
• Major health systems & research institutions

 5. Freelance Nurse Writing

This isn’t a traditional PRN or part-time role, but if you want flexibility over your schedule, freelance writing could be a great option.

You don’t need prior experience, just strong writing skills and a solid understanding of healthcare topics. Nurses who love patient education, breaking down complex information, or writing clinical content can earn extra income by writing for:

• Health blogs
• Medical education companies
• Patient education websites

To start, build a portfolio and apply for gigs on:

• Upwork
• LinkedIn
• Savvy Nurse Writer Job Board Membership
• Niche job boards like Remote Nurse Connection 

6. PRN Biotech & Medical Device Jobs with Local Travel

If you’re open to a little travel, some biotech and medical device companies hire PRN nurses for clinical trials, device training, or data collection. These roles often require occasional fieldwork but allow for remote flexibility when handling documentation and reporting.

If you like a mix of in-person and remote work, this could be a great way to transition away from bedside nursing without giving up all patient interactions.

Companies that have hired PRN nurses for biotech roles:

• IQVIA
• Abbott
• Syneos Health
• Philips BioTel Heart

How Can I Get A Work From Home Nursing Job Part-time or PRN?

Some part-time remote roles are more beginner-friendly, while others require direct experience in the role (not just bedside experience). If you’re serious about landing one of these jobs, you’ll also need to update your resume strategically because the hiring process in 2025 isn’t what it used to be.

Hiring managers and recruiters aren’t interested in a generic resume. And while having 20+ years of bedside experience is impressive, it’s not the only thing hiring managers evaluate for hiring. It’s not that your experience isn’t valuable (it absolutely is!), but they are looking for additional skills, ones that specifically align with their specific remote role. Your resume needs to show how your bedside skills are transferable, aligning with the job description. Don’t just list bedside nursing tasks & duties.

We’ve got more resume tips in this post on how to tailor your resume for remote nursing jobs. 

Having bedside experience doesn’t automatically mean you can jump into a remote nursing job and hit the ground running. We didn’t exactly have Utilization Review 101 in nursing school to learn how to interpret medical necessity review guidelines. Documenting patient care in EPIC is one thing; using that documentation to justify insurance approvals or denials is a whole different skill set. Just like specialty bedside roles require training, so do most remote nursing positions, sometimes even more. Your clinical knowledge IS valuable, but additional skills are also needed for most these roles.

Think about trying to land your first job in the OR or Cathlab straight out of nursing school. Possible? Yes. But competitive? Absolutely. Most hospitals want you to start in a general unit first, build foundational skills, and then transfer into high-demand specialties like the OR or ICU.

The same logic applies to remote nursing jobs. Companies tend to hire full-time nurses first because training takes time, on average, at least six weeks, before new hires are fully independent and meet key performance indicators (KPIs) like accurately applying medical necessity criteria, reviewing clinical documentation for reimbursement compliance, and making case review decisions in alignment with payer policies.

Employers want to invest in nurses who will stick around long enough to get through that learning curve, which is why PRN and part-time remote roles are harder to land without prior experience. But that doesn’t mean they’re impossible. Some remote nursing jobs are easier to transition into from bedside nursing, and if you know where to look, you can find part-time and PRN opportunities without having to jump through quite as many hoops.

Since many companies prioritize full-time hires first, you’ll need to be intentional about your job search. Here are the best ways to improve your chances:

 Your Next Steps Working From Home As a Nurse

Remote nursing isn’t a one-size-fits-all career path, and part-time or PRN opportunities can take time and strategy to land. The key is to be flexible, persistent, and open to different pathways. Most nurses find success by starting with triage roles, gaining experience in hybrid or onsite jobs, or working full-time before transitioning to part-time.

Start by identifying your priorities. Do you want to maintain clinical skills? Avoid long shifts? Have a fully flexible schedule? Once you’ve narrowed that down, you can focus on the best types of remote nursing specialites for your experience level and tailor your resume accordingly.

Need More Help? Check Out These Resources:

• Flexible Remote Nursing Jobs – Lists different types of nursing careers that offer flexible schedules
• Entry-Level Remote Nursing Jobs – Find positions suited for nurses with little to no remote experience.
• HEDIS Nursing Without Experience – Learn how to break into seasonal HEDIS roles.
• Dealing with Remote Nursing Job Rejections – Tips on handling setbacks and improving applications.

Want to Explore Even More Remote Nursing Careers?

Join the Premium Membership to access the Remote Company Directory (700+), where you can filter companies that specifically hire for part-time and PRN remote nursing roles. Inside, you’ll also get:

• Personalized Job alerts so you never miss new openings
• A network of remote nurses to connect with for job leads
• Resume optimization resources to help you stand out from other applicants
• Monthly chat session to get all of your questions answered
• So much more in this membership! 

Not ready for full membership? No problem! We also offer a free membership with access to all of our free guides!

Sign up here to grab all of our freebie guides in one place!

Save Time with the Right Job Board

Finding the right part-time remote nursing job is easier when you have the right tools. Unlike large job boards that flood you with irrelevant listings (and likely scams too), the Remote Nurse Connection Job Board offers:

• Specialty filters designed just for remote nursing jobs
• License matching to help you find jobs you’re actually eligible for
• A streamlined search so you can apply faster

Start searching for part-time and PRN remote nursing jobs today! 

Remote Nurse Connection is proudly Ad-free. All opinions are my own. This post may contain affiliate links, which means I’ll receive a commission if you purchase through my link, at no extra cost to you. As an Amazon Associate, I earn from qualifying purchases. Please read full disclosure here.

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